- The study, conducted in collaboration with the Department of Biomedicine and Prevention at the University of Rome Tor Vergata and Tor Vergata University Hospital, underscores the relevance of polygenic risk scores (PRS) in risk stratification for patients with a genetic predisposition to breast cancer.
This groundbreaking study, led by Professor Giuseppe Novelli from the University of Tor Vergata in collaboration with key members of Veritas' medical-scientific team (Dr. Vincenzo Cirigliano, Dr. Luis Izquierdo, Giuliana Longo, and Bibiana Palao), suggests that PRS, combined with the assessment of known pathogenic variants, can provide a more accurate risk evaluation for both carriers and non-carriers of mutations in genes such as BRCA1, BRCA2, PALB2, and ATM.
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