MIAMI: Ten Democratic White House hopefuls face a significant early test of their presidential timber Wednesday (Thursday in Manila) in America’s biggest political debate in years, with Elizabeth Warren at center stage, arguing that her progressive policies could defeat incumbent Donald Trump.

Millions of voters are expected to watch the two-night affair in Miami, with the climax on Thursday as former vice president Joe Biden — in his third White House bid, but taking the debate stage as frontrunner for the first time — squares off against No. 2 candidate Bernie Sanders and others.